Origionally posted on CRISPR QC’s website: https://crisprqc.com/wp-content/uploads/2024/08/20240806-CRISPR-Cleave-Case-Study-Layout.pdf
Key Takeaways:
- CRISPR QC’s in vitro CRISPR-Cas cleavage assays can streamline CRISPR workflows by identifying optimal gRNAs and Cas proteins early in the process, saving time and resources typically spent on less effective candidates.
- The CRISPR Analytics Platform revealed significant differences in Cas9 protein activity across different vendors.
- In vitro cleavage data from the CRISPR Analytics Platform correlated positively with in vivo editing outcomes in transgenic mosquitoes, increasing customer confidence in proceeding with gene editing designs.
To read the full case study, go to CRISPR QC’s website: https://crisprqc.com/wp-content/uploads/2024/08/20240806-CRISPR-Cleave-Case-Study-Layout.pdf